Effects various adsorbents on mycelium formation and mycophenolic acid production by Penicillium brevicompactum.

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Effects of Phenylglyoxal and N-ethylmaleimide Concentration on Mycophenolic Acid Production by Penicillium brevi-compactum ATCC16024

Mycophenolic acid is a secondary extracellular metabolite of Penicillium strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. The aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concentration in culture medium on mycophenolic acid production by Penicillium brevi-compactum ATCC16024 was investigated. Batch submerged fer...

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Effects of Phenylglyoxal and N-ethylmaleimide Concentration on Mycophenolic Acid Production by Penicillium brevi-compactum ATCC16024

Mycophenolic acid is a secondary extracellular metabolite of Penicillium strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. The aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concentration in culture medium on mycophenolic acid production by Penicillium brevi-compactum ATCC16024 was investigated. Batch submerged fer...

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L-isoleucine Effects on Yield and Productivity of a Batch Fermentation Process for Mycophenolic Acid Production by Penicillium brevicompactum

Mycophenolic acid (MPA) is an antibiotic and immunosuppressive agent has been produced as a secondary metabolite of some fungi species such as Penicillium. In the present work, in the first step, mycophenolic acid production was performed in a fermentation process by Penicillium brevicompactum MUCL 19011 in shake flask using a base medium. Obtained results demonstrated the maximum MPA productio...

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Production of mycophenolic acid by Penicillium brevicompactum—A comparison of two methods of optimization

Production of mycophenolic acid (MPA) by submerged fermentation using the microfungus Penicillium brevicompactum MTCC 8010 is reported here. Screening experiments were used to identify: the suitable media composition; the optimal initial pH; and the optimal incubation temperature to maximize the production of MPA in batch cultures. The initial concentrations of the selected sources of carbon (g...

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Enhanced Mycophenolic Acid Production by Penicillium brevicompactum with Enzymatically Hydrolyzed Casein

Mycophenolic acid (MPA) is a secondary metabolite produced by Penicillium brevicompactum, which has antibiotic and immunosuppressive properties. In this study, the first, mycophenolic acid was produced in a fermentation process by Penicillium brevicompactum MUCL 19011 in shake flask using a base medium. The maximum MPA production, product yield and productivity of process were 1.379 g/L, 18.6 m...

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ژورنال

عنوان ژورنال: Agricultural and Biological Chemistry

سال: 1987

ISSN: 0002-1369,1881-1280

DOI: 10.1271/bbb1961.51.2503